Quantitative evaluation of the FTA-ABS-IgM and VDRL test in treated and untreated syphilis.

IgM rheumatoid factor removal and performance of the FTA-ABS (IgM) test in congenital syphilis.

OBJECTIVE To determine the performance of the FTA-ABS (IgM) test in congenital syphilis after eliminating interference by IgM rheumatoid factor (RF) and preventing competitive inhibition by IgG. DESIGN The FTA-ABS (IgM) test was carried out before and after RF removal (achieved by immunoprecipitation of the IgG) in infants with congenital syphilis and controls. SETTING Newborns delivered in...

Comparison of the VDRL slide, TPI, and FTA-ABS tests in experimental syphilis in rabbits.

The first serological test for syphilis, developed by Wassermann, Neisser, and Bruck (1906), was a complement-fixation test for reagin activity. Many tests for reagin activity have been developed since then, including the Kline, Kahn, Hinton, Kolmer, Mazzini, and VDRL slide tests. However, none of these is absolutely specific for syphilis. The VDRL slide test (Harris, Rosenberg, and Riedel, 194...

Evaluation of a fully automated treponemal test and comparison with conventional VDRL and FTA-ABS tests.

We evaluated analytic performances of an automated treponemal test and compared this test with the Venereal Disease Research Laboratory test (VDRL) and fluorescent treponemal antibody absorption test (FTA-ABS). Precision performance of the Architect Syphilis TP assay (TP; Abbott Japan, Tokyo, Japan) was assessed, and 150 serum samples were assayed with the TP before and after heat inactivation ...

The FTA-ABS test for syphilis. Performance in 1,033 patients.

During the 20th century, screening tests using nontreponemal lipoidal antigens have evolved from the old Wassermann test to such excellent ones as the VDRL and Kahn flocculation tests and the Kolmer complement-fixation test. These tests are easily performed in small laboratories and are almost invariably reactive in patients who have any form of active syphilis other than primary syphilis. Alth...

Evaluation of the sorbents used in the FTA-ABS test.